Nobel Prize in Medicine Awarded to Three Scientists for Immune System Research

  • The 2025 Nobel Prize in Physiology or Medicine was awarded to U.S. scientists Mary Brunkow and Fred Ramsdell, and Japanese scientist Shimon Sakaguchi for their work on peripheral immune tolerance.
  • Peripheral immune tolerance is a mechanism that prevents the immune system from attacking the body’s own tissues while fighting infections.
  • Their work has opened a new field of research and contributed to the development of treatments for cancer and autoimmune diseases.
  • The winners will share 11 million Swedish kronor (~$1.2 million) and receive a gold medal from the King of Sweden.
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